{"product_id":"denovo-plus","title":"Denovo Plus","description":"\u003cp\u003e\u003cstrong\u003eNOTE: Dietary supplements can take up to three months to yield results, it needs to build up in your system. Order accordingly.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDENOVO® PLUS B12 is a dietary supplement used for the metabolic management of low folate \u0026amp; B12 levels associated with symptoms of depression. Patients with symptoms of depression often exhibit low levels of folate \u0026amp; vitamin B12. The human body needs sufficient folate intake to produce the essential neurotransmitters serotonin, dopamine, \u0026amp; norepinephrine. These neurotransmitters alleviate feelings of sadness, anxiety, \u0026amp; gloom. Vitamin B12 helps the body use fats \u0026amp; carbohydrates to create energy, stimulate serotonin production, \u0026amp; reduce stress when taking a minimum of 500 mcg (1\/2 mg) daily\u003cstrong\u003e. \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAge, weight, medications, nutrition, \u0026amp; genetics are among the factors that affect one’s ability to absorb \u0026amp; produce sufficient folate \u0026amp; B vitamins. 16% - 42% of people in the United States lack a necessary enzyme (MTHFR), depending upon ethnicity. The body cannot produce folate \u0026amp; other B vitamins, so when there is a problem with absorption, supplementation is essential.\u003c\/p\u003e\n\u003cp\u003eDENOVO PLUS B12 contains readily absorbable folate (as L-5-methyfolate) \u0026amp; vitamin B12 (as methylcobalamin). This means the body does not require the MTHFR enzyme to absorb the folate in DENOVO PLUS B12. When MTHFR is deficient, the body cannot convert folic acid to usable, active, folate. DENOVO PLUS B12 works to correct the root cause of the problem, not just treat symptoms.the problem, not just treat symptoms.\u003c\/p\u003e\n\u003cp\u003eEach DENOVO PLUS B12 capsule contains 15 mg of (25,000 mcg DFE) folate (as L-5-methyltetrahydrofolate), \u0026amp; 2 mg (2,000 mcg) of vitamin B12 (as methylcobalamin). The recommended daily dosage is one capsule per day, in the morning, which regimen may require up to 14 days for symptom improvement.\u003c\/p\u003e\n\u003cp\u003eWhy Denovo Plus B12? Because Denovo Plus B12 contains an\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eactive folate\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ethat your body can absorb easily and quickly, Denovo Plus B12 is\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003epriced significantly lower\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ethan similar brands, Denovo Plus B12 \u003cstrong\u003edoes not require a prescription\u003c\/strong\u003e, and Denovo Plus B12\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003econtains adequate amounts of folate\u003c\/strong\u003e \u003cstrong\u003e\u0026amp; vitamin B 12\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003efor you to feel results.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDenovo Plus B12 can help symptoms of:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003esadness, anxiety, discouragement, hopelessness, short-temperedness, seasonal \"blues\", gloominess, despair, irritability, stress, tearfulness, hypersensitivity, fatigue, weakness, low energy, and many more!\u003c\/p\u003e\n\u003cp\u003eGluten-free, Sugar-free, Dairy-free, Soy-free, \u0026amp; Dye-free\u003c\/p\u003e\n\u003cp\u003eDenovo does NOT contain any undesirable fungal additives.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eActive Ingredients:\u003c\/strong\u003e  25,000 mcg DFE of Folate (as 15 mg calcium L-5-methyltetrahydrofolate) \u0026amp; 2,000 mcg vitamin B12 (as 2 mg methylcobalamin)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eInactive Ingredients:\u003c\/strong\u003e microcrystalline cellulose, capsule (gelatin, titanium dioxide), vegetable magnesium stearate, \u0026amp; silica.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUses:\u003c\/strong\u003e\u003cb\u003e \u003c\/b\u003eDENOVO® PLUS B12 is a dietary supplement used for the metabolic management of low folate \u0026amp; B12 levels associated with symptoms of depression.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e Protect from heat, light, \u0026amp; moisture. Keep out of reach of children. Do not purchase if seal is broken.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eFolic acid, when administered in daily doses above 0.1 mg, may obscure the detection of B12 deficiency (specifically, the administration of folic acid may reverse the hematological manifestations of B12 deficiency, including pernicious anemia, while not addressing the neurological manifestations). 5-MTHF may be less likely than folic acid to mask vitamin B12 deficiency. Folate therapy alone is inadequate for the treatment of a B12 deficiency. Methylcobalamin is counteracted with the consumption of alcohol. Serum B12 levels may be artificially elevated in patients with alcoholism, liver disease, or cancer. A major depressive episode may be the initial presentation of bipolar disorder. It is generally believed, although not established in controlled trials, that treating such an episode with an antidepressant alone may increase the likelihood of a precipitation of a mixed\/manic episode in patients at risk for bipolar disorder. Denovo® plus B12 is not an antidepressant. However, 5-MTHF has been shown to enhance antidepressant effects of known antidepressants. Caution is recommended in patients with a history of bipolar illness. Patients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder since mood elevation in this population is possible. DENOVO® PLUS B12 should always be used under medical supervision.\u003c\/p\u003e","brand":"Wellness Architecture","offers":[{"title":"Default Title","offer_id":45723691483196,"sku":null,"price":38.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0671\/4186\/1436\/files\/denovopic.avif?v=1782792837","url":"https:\/\/www.wellnessarchitecture.com\/products\/denovo-plus","provider":"Wellness Architecture","version":"1.0","type":"link"}